Fully virulent Bacillus anthracis does not require the immunodominant protein BclA for pathogenesis.
نویسندگان
چکیده
The BclA protein is the immunodominant epitope on the surface of Bacillus anthracis spores; however, its roles in pathogenesis are unclear. We constructed a BclA deletion mutant (bclA) of the fully virulent Ames strain. This derivative retained full virulence in several small-animal models of infection despite the bclA deletion.
منابع مشابه
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عنوان ژورنال:
- Infection and immunity
دوره 75 1 شماره
صفحات -
تاریخ انتشار 2007